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The outcome is what you hope to achieve through intervention.

Outcome

If the intervention is a direct response to the diagnosis, the outcome is the intended effect of the intervention.  Remember, you don't know until you do research the effect of a particular intervention on a patient population.  That's why you're doing research in the first place!

 

So the (O) in PICO is an outcome you want to find or a likely outcome you think you might find.

PICO 1

Problem: Adults with schizophrenia are struggling to graduate from college

P Adults with Schizophrenia
I Supported education
C No supported education
O Higher graduation rates